Methionine Cycle

Glossary

Note. PubChem links provide 2D molecule diagrams and interactive 3D models.

Enzymes:

• CBS - Cystathione beta-synthase
• CDO - Cysteine dioxgenase
  
• CGL - Cystathione gamma-lyase
  
• CSD - Cysteine-sulfinate decarboxylase (a.k.a. Sulfinoalanine decarboxylase)
  
• DHFR - Dihydrofolate reductase
• GCL - Glutamate-cysteine ligase
• GPx - Glutathione peroxidase(s)
  
• GS - Glutathione synthetase
• GSSGR - Glutathione reductase
  
• MAT - Methionine adenosyltransferase
  
• MS - Methionine synthase
• MSR - Methionine synthase reductase
• MTase - Methyltransferase(s)
  
• MTHFR - Methylenetetrahydrofolate reductase
• SAHH - S-Adenosylhomocysteine Hydrolase
• SHMT - Serine hydroxymethyltransferase
• TS - Thimidylate synthase

Substrates / Products:

• ATP - Adenosine triphosphate ( PubChem)
  
• DHF - Dihydrofolic acid (PubChem)
• dTMP - Thymidine monophosphate (PubChem)
• dUMP - Deoxyuridine monophosphate (PubChem)
• GSH - Glutathione (PubChem)
  
• SAH - S-Adenosyl-L-homocysteine
• SAM - S-Adenosyl methionine (aka SAMe, SAM-e, adoMet)
  
• THF - Tetrahydrofolic acid (PubChem)

Co-enzymes:

• NAD+ / NADH - Nicotinamide adenine dinucleotide
• HADP+ / NADPH - Nicotinamide adenine dinucleotide phosphate
  

Co-factors:

• B2 - Vitamin B2 (Riboflavin).
  
• B6 - Vitamin B6. Active form is Pyridoxal Phosphate (PubChem)
• B12 - Vitamin B12. Active form is Methylcobalamin
• Zn - Zinc
  

Colin,
(some time in 2011)

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